ࡱ> )+(7  bjbjUU "7|7| lxxxx   h j j j j j j $  V   $h h xh h  O\x h h 0 h MMh Hypoadrenocorticism, also called Addison's disease, is an endocrine disorder that results from a deficient production of adrenal gland hormones. There are two adrenal glands in the abdomen that lie just in front of the kidneys. The most common cause of Addison's disease in the dog is destruction of the adrenal gland tissue by the animal's immune system. Infrequently, certain infections, medications, cancer or diseases of the pituitary gland may also cause Addison's disease. Addison's disease may also be caused by the abrupt discontinuation of steroid medication. Dogs that have been on long-term steroids should be slowly weaned off such drugs. Abruptly stopping the medication can result in an Addisonian crisis. Addison's disease is an uncommon disorder in dogs and is extremely rare in cats. It is thought to be familial and inherited in Leonbergers, standard poodles, and Nova Scotia duck tolling retrievers. Certain other breeds may also be predisposed, such as the Airedale, bearded collie, German shepherd dog, German shorthair pointer, Great Dane, St. Bernard, English springer spaniel, West Highland white terrier, wheaten terrier, and Portuguese water dog. Hypoadrenocorticism most often affects young to middle-aged dogs. About 70 percent of affected dogs are female. Neutered male dogs are more likely to develop hypoadrenocorticism than intact male dogs. In hypoadrenocorticism there is usually a deficiency of two different groups of hormones, the glucocorticoids and the mineralocorticoids. The primary glucocorticoid hormone is cortisol, and it is responsible for combating stress, helping to maintain  HYPERLINK "http://www.petplace.com/dogs/hypoadrenocorticism-addison-s-disease-in-dogs/page1.aspx" \t "_new" blood sugar. The major mineralocorticoid is aldosterone. Aldosterone regulates the water, sodium, potassium, and chloride concentrations in the body. Most naturally occurring forms of Addison's disease affects both hormones. Addison's disease secondary to the abrupt withdrawal of steroid medications affects only the level of circulating cortisol. What to Watch For The clinical signs seen with Addison's disease are somewhat variable. They may be mild and very vague initially. With an acute crisis, the signs are more pronounced and profound. Clinical signs include: Lethargy, weakness Poor appetite Vomiting Weight loss Depression Dehydration Diarrhea Excessive thirst and water intake (polydipsia) Vomiting Diarrhea Low body temperature, shaking, collapse, low heart rate b c 1 B 5B*\aJph0JB*aJphjB*UaJph B*aJph B*phB*CJOJQJph  G R    1h/ =!"#$% i8@8 NormalCJ_HaJmH sH tH <A@< Default Paragraph FontO klink&O& preloadwrap@B@@ Body TextB*CJOJQJaJph333.U@!. Hyperlink >*B*ph8':^@2: Normal (Web)dd[$\$  G R 000000000   b XT!*T_AI;Nk~    %-aj    ASHRAF GOMAAIC:\Documents and Settings\MOHSEN GOMAA\Desktop\Abbott Web\hypoT4 dogs.doc ASHRAF GOMAAIC:\Documents and Settings\MOHSEN GOMAA\Desktop\Abbott Web\hypoT4 cats.doc ASHRAF GOMAAJC:\Documents and Settings\MOHSEN GOMAA\Desktop\Abbott Web\hyperT4 cats.doc ASHRAF GOMAAlC:\Documents and Settings\MOHSEN GOMAA\Application Data\Microsoft\Word\AutoRecovery save of hyperT4 cats.asd ASHRAF GOMAAFC:\Documents and Settings\MOHSEN GOMAA\Desktop\Abbott Web\cat ears.doc ASHRAF GOMAADC:\Documents and Settings\MOHSEN GOMAA\Desktop\Abbott Web\DI dog.doc ASHRAF GOMAANC:\Documents and Settings\MOHSEN GOMAA\Desktop\Abbott Web\hyperadrenal dog.doc ASHRAF GOMAANC:\Documents and Settings\MOHSEN GOMAA\Desktop\Abbott Web\hyperadrenal cat.doc ASHRAF GOMAAMC:\Documents and Settings\MOHSEN GOMAA\Desktop\Abbott Web\hypoadrenal dog.doc@$$TD$$ @UnknownGz Times New Roman5Symbol3& z Arial7&  Verdana"qh馯m$!xr0 2Q~Hypothyroidism is a disorder of the thyroid gland, which is the butterfly-shaped glandular organ located in the neck just belo ASHRAF GOMAA ASHRAF GOMAAOh+'0 ,DP\l    Hypothyroidism is a disorder of the thyroid gland, which is the butterfly-shaped glandular organ located in the neck just beloypo ASHRAF GOMAAm iSHRSHRNormalG ASHRAF GOMAAm i2HRMicrosoft Word 9.0 @ @\@\m$՜.+,D՜.+,h hp|  G /  Hypothyroidism is a disorder of the thyroid gland, which is the butterfly-shaped glandular organ located in the neck just belo Title, 8@ _PID_HLINKSA\Vhttp://www.petplace.com/dogs/hypoadrenocorticism-addison-s-disease-in-dogs/page1.aspx !"#$%&'*Root Entry FO\,1TableWordDocument"SummaryInformation(DocumentSummaryInformation8 CompObjjObjectPoolO\O\  FMicrosoft Word Document MSWordDocWord.Document.89q